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AIHOT · Published on November 4, 2026 at 01:05

Rohan Paul reviews Intology Locus: An automated research system outperforms GPT-6 Astra and Claude Opus 5.5 agents in molecular design tasks.

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Rohan Paul comments on Intology's automated research system Locus, stating it surpasses GPT-6 Astra and Claude Opus 5.5 agents in molecular prediction tasks. Locus performs the work of a machine learning researcher: proposing experiments, running multiple batches in parallel on GPUs, retaining valid results, and iterating; currently applied to drug and antibody design; cited content notes its performance in molecular property prediction, fine-tuning Boltz-2 for small molecule potency prediction, and workflows around BoltzGen, Boltz-2, ESMC, and ESMFold2 for antibody design...

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